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4.2.1.3 Microarray Data Transformation After the numerical readings are obtained from the image, the objective of microarray data transformation is to identify outliers in the data and to adjust the data to meet the distribution assumptions implied by statistical analysis methods. A simple logarithmic transformation illustrated in Figure 4.6 is commonly used. It reshapes the data distribution into a bell shape that resembles normal distribution. This transformation is especially bene cial for data from dual-channel arrays, since data from these arrays are often expressed as ratios of signal intensities of pairs of samples. Alternative transformations used in practice include arcsinh function, linlog transformation, curve- tting transformations, and shift transformation [9]; among them, the linlog transformation was demonstrated to be the most bene cial. 4.2.2 Handling Missing Values rdlc pdf 417 PDF417 Barcode Creating Library for RDLC Reports | Generate ...
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Free trial package available to insert PDF - 417 barcode image into Client Report RDLC . Graphically, the Sharpe Ratio is the slope of the line from the risk-free rate to the portfolio in question. Exhibit 8.11 shows two portfolios. I know that the Sharpe Ratio for Portfolio 2 is higher than that for Portfolio 1, because the slope of the line to Portfolio 2 is higher than the slope of the line to Portfolio 1. Finally, let s look at the relation between the Sharpe Ratio and the ef cient frontier. In Exhibit 8.12, Portfolios 1 and 2 have the same level of risk. Note that the Sharpe Ratio is higher for Portfolio 2 than for Portfolio 1. Also note that there is no feasible portfolio with this risk level that has a higher expected return. What this means is that points on the ef cient frontier represent the highest Sharpe Ratio for that level of risk. Put another way, every point on an ef cient frontier is a maximum Sharpe Ratio the maximum Sharpe Ratio for that level of risk. So it follows that if you have the maximum Sharpe Ratio, you will be on the ef cient frontier. rdlc pdf 417 How to add Barcode to Local Reports ( RDLC ) before report ...
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